As new Covid variant revives old fears, is India prepared?
India must deploy a calibrated response: sustained surveillance, protection of the vulnerable and awareness that cuts through panic and misinformation
COVAXIN is India's homegrown COVID-19 vaccine developed by Bharat Biotech in collaboration with the Indian Council of Medical Research (ICMR) - National Institute of Virology (NIV). It is a two-dose vaccine administered within a gap of few weeks.
The inactivated vaccine, which uses adjuvant Alhydroxiquim, is developed and manufactured in Bharat Biotech's BSL-3 (Bio-Safety Level 3) high containment facility.
Whole-Virion inactivated vero cell derived platform technology is used for developing COVAXIN. Inactivated vaccines are unlikely to revert and cause pathological effects and do not replicate. The vaccine is made up of killed coronaviruses and when administered, it prompts the immune system to build antibodies against the virus and does not cause any infection.
Bharat Biotech claimed that COVAXIN shows an interim efficacy of 81 per cent in its phase 3 clinical trials. COVAXIN was approved by the Drugs Controller General of India (DCGI) for restricted emergency use in January 2020. A controversy also erupted after the vaccine was cleared for emergency use while its trials were still underway.
In July 2020, DGCI gave its nod to COVAXIN to conduct phase I and phase II clinical human trials. After the completion of phase II interim analysis, Bharat Biotech said that the vaccine has 78 per cent efficacy against mild, moderate and severe Covid-19 disease.
The vaccine can be stored at temperature ranging from2 to 8 degree Celsius and includes immune-potentiates to boost its immunogenicity.
According to Bharat Biotech, COVAXIN is effective against variants of concern and demonstrates 65.2 per cent protection against the SARS-CoV-2, B.1.617.2 delta variant.
India must deploy a calibrated response: sustained surveillance, protection of the vulnerable and awareness that cuts through panic and misinformation
Covid-19 cases are rising again in India with new variants spreading across multiple states. Despite halted vaccine production, officials confirm a sufficient stockpile to meet current and future needs.
Bharat Biotech announced that it is adding the Indian Council of Medical Research (ICMR) as a co-owner of the Covaxin patent, citing an 'unintentional' omission in the original filing.
ICMR's director criticised the study about Covaxin's side effects, citing its poor methodology and design, and clarified that the article misleadingly "acknowledges" India's apex medical research body.
Amid a row over AstraZeneca's admission of potential side effects of its Covid-19 vaccine, Bharat Biotech said that its Covaxin vaccine was developed with a single-minded focus on safety first, followed by efficacy.
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Vivek Agnihotri's latest project 'The Vaccine War' is all set for its theatrical release on September 28. Vivek, along with Nana Patekar and Pallavi Joshi, in an exclusive interview with India Today, discussed how the Indian scientists who made Covaxin should be celebrated.
Last month, Covid-19 Working Group headed by Dr N K Arora had also recommended to the health ministry inclusion of Covovax on the CoWIN portal as a heterologous booster dose for adults who have been vaccinated with two doses of either Covishield or Covaxin.
Since the beginning of the pandemic till now, here’s a look at what India did right in bringing Covid-19 under control.
The Centre termed as "misleading" and "fallacious" media reports which claimed that regulatory approval for Covaxin was rushed due to political pressure. Bharat Biotech also stated that there was no external pressure to accelerate development of Covaxin.
The Centre approved Biological E's Corbevax as a precaution dose for those above 18 years fully vaccinated with either Covishield or Covaxin.
In a first, the government has approved Biological E's Corbevax as a precautionary dose for those above 18 years fully vaccinated with either Covishield or Covaxin.
The Standing Technical Sub-Committee (STSC) of NTAGI recommended the use of Biological E manufactured Corbevax and Bharat Biotech's Covaxin for children aged between 5-12 years.
According to a study conducted by the ICMR, Covaxin as a booster dose enhances vaccine effectiveness against Covid-19’s Delta and Omicron variants.
Bharat Biotech has sought DCGI’s approval to conduct phase 2/3 trial of its Covid-19 vaccine Covaxin as a booster shot among children aged 2-18 years old.
The Drugs Controller General of India has granted Bharat Biotech the permission to use Covaxin for those aged 6 to 12 years.
The government panel recommended granting approval to Biological E's Covid-19 vaccine Corbevax for use in children in 5 to 12 years age group.
The Centre announced earlier this week that all adults can get their Covid-19 vaccine precaution (third) doses from April 10 onwards. Are you eligible for it? How much will it cost? Here's everything you need to know.
Private hospitals will now be able to buy a single dose of Covid-19 vaccines Covishield and Covaxin at Rs 225.
The government has said that Covid-19 vaccine beneficiaries do not need to register on the CoWIN portal again for their precaution doses. The government added that private centres administering booster doses can levy a maximum of Rs 150 as service charge.
Medical experts discuss the alleged connection between COVID-19 vaccines and heart attacks, firmly stating there is no scientific evidence to support such claims.
The transcript features a discussion with two medical experts, Dr. Kunal Sarkar and Dr. Subramaniam Swaminathan, about the perceived link between COVID-19 vaccines and heart attacks. They emphasize that there is no authenticated data supporting a correlation between COVID vaccination and increased heart attacks. The experts highlight India's high incidence of cardiac problems due to factors like diabetes, hypertension, and lifestyle issues. They discuss studies showing that respiratory viral infections can trigger cardiac events, and that flu vaccines may actually reduce the risk of death in heart attack patients. The conversation also touches on the need for better recording of vaccine side effects in India and the importance of lifestyle changes to prevent heart problems.
India will likely begin inoculating children in the 12-14 age groups against Covid from March as the 15-18 population will mostly be fully vaccinated by then, Dr NK Arora, Chairman of the Covid-19 working group NTAGI, said on Monday. Of the estimated 7.4 crore children in the 15-18 age bracket, over 3.45 crore have already received the first dose of Covaxin so far and their second dose is due in 28 days, he said.
As Covid-19 cases, including those of the Omicron variant, rapidly rise in India, the next leg of the nation’s vaccination drive started on Monday. Vaccination for children aged 15-18 years began across the country on Monday. The CoWIN app had already recorded over six lakh registrations by Sunday evening. The vaccine option for this age group is the indigenously-developed Covaxin. The Centre has advised states and UTs to provide separate vaccination centres, session sites, queues and different vaccination teams for the 15-18 year age group.
As India gears up to vaccinate 15 to 18 year olds from January 3, the CoWIN app has already recorded over six lakh registrations till Sunday evening. The vaccine option for this age group would be indigenously-developed Bharat Biotech’s Covaxin.